End-stage renal disease ,ESRD
Conditions
Interventions
Experimental group:General anesthesia will be induced and maintained with remimazolam.
Control group:General anesthesia will be induced and maintained with propofol.
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Preoperative complications with end-stage renal disease: eGFR < 30 mL/min/1.73m2; 3. Scheduled to undergo elective sugery; 4. Sign an informed consent form before surgery.
Exclusion criteria
Exclusion criteria: 1. Emergent surgery; 2. Benzodiazepines were taken continuously for more than 1 week within 1 month before surgery; 3. History of schizophrenia ,epilepsy ,Parkinson's disease, or myasthenia gravis; 4. Inability to communicate due to coma, severe dementia, or language impairment; 5. Organ transplantation surgery or urologic Surgery; 6. ASA physical status classification >= 4, severe liver dysfunction (Child-Pugh class C); 7. Other reasons that are considered unsuitable for study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 score;Days alive and at home in the first 30 days after surgery: DAH30; | — |
Countries
China
Contacts
Public ContactJiaojiao Niu
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed