Extubation stress response
Conditions
Interventions
experimental group:Use ordinary endotracheal tube to intubate through visual laryngoscope, and spray 2 ml of 2% lidocaine after exposing glottis
expermental group 1:The drug injection endotracheal tube was intubated through the visual laryngoscope. 2 ml of 2% lidocaine was injected into the upper and lower glottis through the tube immediately
expermental group 2:The drug injection endotracheal tube was intubated through the visual laryngoscope. Immediately after intubation and 5 minutes before the end of the operation, 2 ml of compound bet
Sponsors
Neijiang First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing tracheal intubation under elective general anesthesia; 2. ASA anesthesia grade I-II; 3. Aged 18-60 years, body mass index (BMI) < 30 kg/m2; 4. The operation time is more than 2 hours, and the catheterization is successful through one operation within 30 s under the visual laryngoscope.
Exclusion criteria
Exclusion criteria: 1. Patients with hypertension, diabetes, coronary heart disease and respiratory diseases in unstable period; 2. Those with throat pain or inflammation before intubation; 3. Those with pharyngeal anatomy and pathological changes; 4. Communication disorder caused by language function defect or consciousness disorder, mental disease and other reasons; 5. Family members or patients do not agree to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemodynamic parameter;cortisol;Riker sedation and agitation score; | — |
Countries
China
Contacts
Public ContactWu Ailing
Neijiang First People's Hospital
Outcome results
None listed