FindTrial
Sign In

Effect of Postextubation Noninvasive Ventilation or High-Flow Nasal Oxygen vs Conventional Oxygen Therapy on Reintubation Among Patients at High Risk of Extubation Failure

Effect of Postextubation Noninvasive Ventilation or High-Flow Nasal Oxygen vs Conventional Oxygen Therapy on Reintubation Among Patients at High Risk of Extubation Failure

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061820
Enrollment
Unknown
Registered
2022-07-03
Start date
2022-06-20
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reintubation

Interventions

control group:conventional oxygen therapy
treatment group:Noninvasive ventilation or high-flow nasal oxygen

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Older than 65 years old; 2. Endotracheal intubated >= 24 hours; 3. Successfully pass the spontaneous breathing test; 4. Planned extubation, and non-invasive ventilation or high-flow nasal catheter oxygen inhalation or continuous oxygen therapy was used immediately after extubation.

Exclusion criteria

Exclusion criteria: 1. Tracheotomy; 2. Unplanned extubation; 3. Non-cooperation or refusal to reintubate; 4. Underlying chronic neuromuscular diseases; 5. Traumatic brain injury leading to intubation; 6. Transfer within 48 hours after admission to ICU.

Design outcomes

Primary

MeasureTime frame
reintubation;—

Secondary

MeasureTime frame
respiratory failure;length of study in ICU;length of study in hospital;—

Countries

China

Contacts

Public ContactShuliang Guo

The First Affiliated Hospital of Chongqing Medical University

guosl999@sina.com+86 13101363078

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026