Effect of minimum driving pressure guided individualized ventilation strategy on pulmonary function in elderly patients undergoing laparoscopic colorectal cancer surgery

Application of pressure driven individualized ventilation strategy in elderly patients undergoing laparoscopic colorectal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200061811

Enrollment

Unknown

Registered

2022-07-03

Start date

2022-07-27

Completion date

Unknown

Last updated

2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Test group:Minimum driving pressure oriented individualized peep

Control group:Traditional fixed PEEP lung protection strategy

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing laparoscopic radical surgery for colorectal cancer; 2. Aged 60-80 years; 3. ASA II-III.

Exclusion criteria

Exclusion criteria: 1. Patients with diseases affecting respiratory function before operation, including neuromuscular diseases, severe pulmonary bullae, pneumothorax, pleural effusion, severe obesity, body mass index >= 35 kg/m2; 2. Uncontrolled hypertension, diabetes and other chronic diseases; 3. Chronic obstructive pulmonary disease or cor pulmonale; 4. Abnormal cardiac function; 5. Difficult airway; 6. Patients with mental diseases or serious anxiety and depression.

Design outcomes

Primary

Measure	Time frame
7-day PPCS incidence rate (= level 2);	—

Secondary

Measure	Time frame
A-ADO2;Vd/Vt;Oxygen index;Intraoperative vital signs;PACU stay time;Hospital stay;Operation time;Intraoperative lung compliance indicators;	—

Countries

China

Contacts

Public ContactYi Zheng

Wenzhou People's Hospital

zhengymz@126.com+86 150 8858 6887

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026