cataract
Conditions
Interventions
two:drug treanment
control group:0.1% pramiphene eye drops
Sponsors
Qingdao Eye Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients volunteer as subjects aged 40-85 years who were diagnosed with age-related cataract and required microincision phacoemulsification and intraocular lens implantation; 2. According to the CATARACT LOCSIII grading method, patients with grade II-III crystal nucleus hardness.
Exclusion criteria
Exclusion criteria: 1. Previous glaucoma, uveitis, fundus lesions, corneal maculus, positive corneal fluorescence staining and other ocular diseases; 2. Previous history of eye trauma; 3. Suffer from systemic diseases such as diabetes and autoimmune diseases; 4. Posterior capsule rupture, vitreous prolapse and other accidents occurred during the operation; 5. Unable to cooperate with the completion of preoperative examination and unable to ensure timely completion of follow-up requirements after surgery; 6. Had oral, injection or external use of steroid hormones, non-steroidal anti-inflammatory drugs, immunosuppressive drugs and other anti-inflammatory drugs within 1 month; 7. Patients with serious heart, lung, liver and renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory biomarkers;The clinical symptoms;Dry eye related detection;Corneal fluorescence staining; | — |
Secondary
| Measure | Time frame |
|---|---|
| Noncontact intraocular pressure;Drug safety and adverse reactions; | — |
Countries
China
Contacts
Public ContactYusen Huang
Qingdao Eye Hospital of Shandong First Medical University
Outcome results
None listed