hepatoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: This study was approved by the ethics committee of the second hospital of Shandong University 1. all patients or family members signed informed consent; 2. Patients with liver cancer undergoing selective hepatectomy under general anesthesia combined with costal QLB were selected; 3. all of patients used sufentanil for postoperative analgesiathe age raged from 18-75 years; 4. ASA grade I-III.
Exclusion criteria
Exclusion criteria: 1. Preoperative cognitive impairment; 2. history of severe hypertension or heart disease; 3. Liver and kidney dysfunction; 4. Blood system diseases and abnormal bleeding and coagulation; 5. BMI> 30kg/m^2; 6. Distant organ metastasis; 7. Recent use of antidepressants, sedatives or analgesics; 8. History of previous abdominal surgery; 9. Recent history of radiotherapy and chemotherapy intraoperative operation was changed to open operation; 10. In patients undergoing nerve block, there were regional block complications such as puncture site injury, infection and bleeding and local anesthetic poisoning; 11. Failed to complete data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor recurrence, metastasis and death within 3 years after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative rest pain and activity pain were evaluated by NRS;Postoperative analgesic dosage, out of bed time,drainage flow, time for drainage tube extraction;Adverse reaction; | — |
Countries
China
Contacts
The second hospital of Shandong University