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Clinical Observation on Prevention and Treatment of Hashimoto's Thyroiditis with External Use of 'Xiaoying Paste'

Clinical Observation on Prevention and Treatment of Hashimoto's Thyroiditis with External Use of 'Xiaoying Paste'

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061762
Enrollment
Unknown
Registered
2022-07-02
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hashimoto's thyroiditis

Interventions

Treatment Group:Xiaoying Paste
Control Group:Palliative care

Sponsors

Shanghai Municipal Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Western diagnostic criteriaAccording to the standard of "Chinese Guidance for diagnosis and Treatment of Thyroid Diseases" issued by Chinese Society of Endocrinology. (1) Goiter, toughness enhancement, or isthmus large or asymmetric, or with nodules; (2) Typical clinical manifestations,TPOAb or TGAb positive. 2. Diagnostic criteria of TCMRefer to the diagnostic criteria for gall disease in "Guidelines for Clinical Research on New Chinese Medicines (Trial)".Main symptoms: neck discomfort or swelling, palpitations, irritability, fatigue.Secondary symptoms: dry mouth, thirst, overeating, forgetfulness, constipation or weak defecation, red or pale tongue, thin white or greasy tongue coating, stringy or fast pulse. 3. Those who meet the above diagnostic criteria and the serum TGAb and TPOAb indicators are within the measurable range and subclinical hyperthyroidism, hypothyroidism, and normal thyroid function. 4. The patients are conscious, voluntarily participate in the study and sign the informed consent. 5. Age > 18.

Exclusion criteria

Exclusion criteria: 1. Those with goiter compressing adjacent organs or with thyroid heart disease; 2. Patients with goiter with exophthalmus,TGAb(+), and TPOAb titer slightly increased and diagnosed with other thyroid diseases; 3. Serious complications of heart, liver, kidney and other organs and diseases of blood system; 4. Pregnant or breastfeeding women; 5. Those with allergic constitution; 6. Those with poor compliance, quitting halfway, and incomplete data, but those with adverse reactions were counted.

Design outcomes

Primary

MeasureTime frame
FT3;FT4;TSH;TGAb;TPOAb;

Secondary

MeasureTime frame
TNF-a;IL-6;IL-10;INF-y;

Countries

China

Contacts

Public ContactYi Zhang

Shanghai Traditional Chinese Medicine Hospital

zhangyizhongyi001@163.com+86 18116070306

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026