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Application of a new type of high-flow humidified oxygen therapy device to improve pulmonary function in patients with respiratory failure

Application of a new type of high-flow humidified oxygen therapy device to improve pulmonary function in patients with respiratory failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061752
Enrollment
Unknown
Registered
2022-07-02
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with respiratory failure

Interventions

intervention group:Use NTHF (connect the oxygen suction tube, Venturi, Fisher & Paykel MR850 heated humidifier, RT308 breathing tube with humidification tank, closed suction tube and tracheotomy in se
control group:Using AIRVOTM2 (Fisher & Paykel, Auckland, New Zealand), connect the special breathing circuit, tracheostomy connector and tracheostomy tube in sequence from the output end of the oxygen

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. The age of the patient is >= 18 years old and meets the diagnostic criteria for respiratory failure; 2. Have an artificial airway, ready or have been released from the ventilator; 3. The circulation is basically stable, and there is no shock of various types that is difficult to correct (mean arterial pressure is still <65 mmHg under the condition of vasoactive drugs); 4. Consciousness and ability to cooperate with clinical treatment.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Pregnancy and end-stage cancer patients; 2. History of airway injury, pulmonary trauma, and lung surgery; 3. Central respiratory failure or status asthmaticus caused by neurological diseases; 4. Refusing to cooperate with treatment or to participate in the researcher.

Design outcomes

Primary

MeasureTime frame
Oxygenation Index;

Secondary

MeasureTime frame
Pulmonary ventilation function index;blood gas analysis;hemodynamic index;Microbial metagenomic sequencing;

Countries

China

Contacts

Public ContactMei Yang

Shenzhen Second People's Hospital

Yangmei3056@163.com+86 13509682339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026