H- hypertension
Conditions
Interventions
accurate group:Based on the appropriate dose of folic acid according to the genotype of the patient, the pharmacist will conduct regular follow-up visits in accordance with the expert Consensus on Fam
Regular group:The clinician gave folic acid dose according to clinical experience, pharmacists did not follow up.
Sponsors
Changzhi People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with H type hypertension; 2. Be able to understand the purpose of the test and sign the informed consent voluntarily; 3. The patients were between 18-75 years old, with no gender limitation.
Exclusion criteria
Exclusion criteria: 1. Patients under the age of 18; 2. Patients who have participated in other clinical research projects; 3. Long-term use of anticoagulant drugs (such as atrial fibrillation, valve replacement, chronic obstructive pulmonary disease, etc.); 4. There are obvious other abnormal signs, laboratory tests and clinical diseases, according to the judgment of the investigator, are not suitable to participate in the investigator; 5. Patients with malignant tumors, genetic diseases and autoimmune diseases; 6. Patients with severe mental illness or inability to express their wishes; 7. People with allergic constitution, or people known to be allergic to therapeutic drugs; 8. Pregnant or lactating women; 9. Patients who are taking enalapril folic acid tablets or regular folic acid tablets; 10. Patients who are unwilling to fill in informed consent, or are unwilling to accept follow-up visits, or have poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HCY LEVEL;MTHFR Genetype; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory examination;Adverse events; | — |
Countries
China
Contacts
Public ContactChunxia Hou
Outcome results
None listed