Effects of optimal PEEP titrated by EIT during robotic-assisted laparoscopic hepatobiliary and pancreatic surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200061726

Enrollment

Unknown

Registered

2022-07-01

Start date

2021-04-01

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

The best PEEP group:Ventilated with the best PEEP titrated by EIT

Traditional PEEP group:Ventilated with PEEP of 5 cmH2O

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for robotic-assisted laparoscopic hepatobiliary surgery under general anesthesia; 2. Scheduled surgery duration longer than 180 minutes; 3. Adult patients (age 18 years or above); 4. American Society of Anesthesiologists Physical Status ?-?; 5. Body mass index 18-35kg/m2.

Exclusion criteria

Exclusion criteria: 1. Pregnancy; Enrolled in other interventional studies; Pneumonia in the previous 30 days; 2. Chronic obstructive pulmonary disease (COPD) GOLD grades III and IV, lung fibrosis, documented bullae, severe emphysema or pneumothorax; uncontrolled asthma; 3. pulmonary hypertension; previous lung surgery; 4. heart failure; New York Heart Association grade 3 and 4 or coronary heart disease Canadian Cardiovascular Society grade 3 and 4; 5. neuromuscular disease (e.g., thymoma, myasthenia, myopathies, muscular dystrophies); other severe systemic diseases.

Design outcomes

Primary

Measure	Time frame
Respiratory Mechanics Parameters;	—

Secondary

Measure	Time frame
Oxygenation;Hemodynamics parameters;Postoperative Pulmonary Complicantions;Atelectasis;	—

Countries

China

Contacts

Public ContactChangsheng Zhang

powerzcs@126.com+86 13810046301

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026