pediatric obstructive sleep apnea
Conditions
Interventions
Test group:The adenotonsillectomy and postoperative functional therapy using Twin-Block appliance
Active control group:The functional therapy using Twin-Block appliance(the adenotonsillectomy was performed if necessary after functional therapy)
Sponsors
School and Hospital of Stomatology, Wuhan University
Eligibility
Sex/Gender
All
Age
8 Years to 14 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria are as follows: 1. Patients aged 8 to 14 years, who are at the peak of puberty (CVM stage 3) or before. 2. Patients with class II division 1 relationship, skeletal class II malocclusion and mandibular retraction (ANB>= 4°, overjet of 5 mm or more); 3. Patients with no obvious symptom of temporomandibular disorders; 4. Patients with oral breathing or snoring during sleep, diagnosed with mild to moderate OSA (apnoea hypopnoea index (AHI) 1~10 events per hour during a period of not less than 7 hours of consecutive sleep according to PSG measurement); 5. Patients diagnosed with hypertrophy of adenoid and (or) tonsil by otorhinolaryngologist, eligible for the adenotonsillectomy. 6. Patients who were willing to participate in the study and had written informed consent from their caregivers; 7. Patients with good dental health.
Exclusion criteria
Exclusion criteria: The exclusion criteria are as follows: 1. Patients with acute upper respiratory infection. 2. Patients with body mass index (BMI) above cut off points of overweight(BMI> 25kg/m^2). 3. Patients diagnosed with severe OSA (AHI> 10/h). 4. Patients with previous adenotonsillectomy or orthodontic treatment. 5. Patients with craniofacial abnormality, neuromuscular disease and cardiopulmonary disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ANB angle;Apnea/Hypopnea Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| The morphologic change in upper airway dimension;lowest oxyhemoglobin saturation (LSaO2);Quality of life (subjective symptoms);Oral Health-related Quality of Life; | — |
Countries
China
Contacts
Public ContactHong He
School and Hospital of Stomatology, Wuhan University
Outcome results
None listed