Nasopharyngeal carcinoma
Conditions
Interventions
Observation group:Symptomatic treatment
Prevention group:Prophylactic eustachian tube blowing
Treatment group:Therapeutic eustachian tube blowing
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years, male or female; 2. According to the eighth edition of ACJJ (2017 edition), NPC is classified into stage I~IVA; 3. Patients with indications for radiotherapy and planning to receive radiotherapy; 4. NPC patients with normal subjective evaluation and objective examination of eustachian tube function and auditory function before radiotherapy; 5. The subjects voluntarily participated in the study and signed informed consent with good compliance and follow-up.
Exclusion criteria
Exclusion criteria: 1. NPC patients who have received radiotherapy; 2. Eustachian tube dysfunction and hearing impairment confirmed by subjective or objective examination; 3. NPC patients with ear diseases such as tympanic membrane perforation and chronic otitis media; 4. Pregnant or lactating women; 5. Those who have a history of psychotropic drug abuse and cannot get rid of it or have mental disorders; 6. Patients who have also participated in clinical trials of other anticancer drugs; 7. Patients with concomitant diseases that, according to the judgment of the investigator, seriously endanger the patient's safety or affect the patient's ability to complete the study; 8. The researcher considered it unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TMM eustachian tube function test;acoustic immittance;electric listening test;the seven-item Eustachian Tube Score;the seven-item Eustachian Tube Dysfunction Questionnaire score;Otoendoscopy;Nasal endoscopy;CT examination of eustachian tube; | — |
Countries
China
Contacts
Public ContactYe Jing
The First Affiliated Hospital of Nanchang University
Outcome results
None listed