coronary heart disease
Conditions
Interventions
Nicorandil group:Before PCI, a single oral dose of nicorandil 20mg and a long-term oral dose of nicorandil 5mg were given three times a day
control group:Routine oral loading dose of aspirin 300mg, clopidogrel 600mg or tigritol 180mg before PCI
Sponsors
Shanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. New onset chest pain within 12 hours (acute myocardial infarction with cardiogenic shock within 18 hours), chest pain lasting for more than 30 minutes; 2. ECG findings: (1) ST segment arcuate back elevation newly appeared after J point of at least two adjacent leads [V2-V3 leads >= 0.25 mV (male aged = 0.2 mV (male aged >= 40 years) or >= 0.15 mV (female), other adjacent chest leads or limb leads >= 0.1 mV] with or without pathological Q wave and R wave reduction; (2) New complete left bundle branch block; (3) T wave changes in hyperacute phase; 3. With or without elevated troponin I.
Exclusion criteria
Exclusion criteria: 1. Patients with severe vascular stenosis who cannot undergo PCI or need emergency bypass; 2. Those who received thrombolytic therapy before hospital; 3. Those who died within 24 hours after admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| thrombolysis in myocardial infarction blood flow classification;index of micro-circulation resistance;Wall Motion Score Index;left ventricular ejection fraction; | — |
Countries
China
Contacts
Public ContactCheng Gong
Shanxi Provincial People's Hospital
Outcome results
None listed