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Clinical research of cryotherapy in reducing postoperative endodontic pain

Clinical research of cryotherapy in reducing postoperative endodontic pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061669
Enrollment
Unknown
Registered
2022-06-30
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpitis and apical periodontitis

Interventions

group 1:Pulpitis: Intra-canal cryotherapy (0°C saline for final irrigation)
group 2:Pulpitis: Intra-canal cryotherapy (2.5°C saline for final irrigation)
group 3:control group: Intra-canal cryotherapy (25°C saline for final irrigation)
group 4:Apical periodontitis: Intra-canal cryotherapy (0°C saline for final irrigation)
group 5:Apical periodontitis: Intra-canal cryotherapy (2.5°C saline for final irrigation)
group 6:Apical periodontitis: Intra-canal cryotherapy (25°C saline for final irrigation)

Sponsors

Guo Jihua
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. No systemic diseases and allergic reactions; 2. Aged 18-50 years, gender is not limited; 3. Inform the research purpose and design before surgery, and sign the informed consent; 4. Root canal treatment is required for pulpitis and apical periodontitis diagnosed by clinical and imaging examinations; 5. The apical foramen is closed; 6. Preoperative Visual Analog Scale (VAS) (0-10 points, clinical evaluation with "0" as "no pain at all", "1-3" as "slight pain", "4-6" as "moderate pain", "7-9" is divided into "severe pain", and "10" means "most unbearable pain"). Patients were evaluated for preoperative pain according to the intensity of pain, and those with scores above 6 were included in the study.

Exclusion criteria

Exclusion criteria: 1. Use of any type of pain reliever or antibiotic medication within 3 days; 2. Root canal therapy has been performed; 3. Severe periodontal disease, there is a periodontal pocket > 3 mm in the affected tooth; 4. Anatomical abnormalities such as excessively curved roots, too long or too short root lengths, problems in determining working length. Root canal calcification, etc.; 5. Patients with unclosed apical foramen or with root resorption; 6. Patients who refused to participate in the study or had incomplete information on the pre-study form.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
Use of painkillers after root canal theratment;The incidence of postoperative endodontic pain;

Countries

China

Contacts

Public ContactGuo Jihua

School of Stomatology, Wuhan University

jihuaguo@whu.edu.cn+86 18971148701

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026