hepatocellular carcinoma
Conditions
Interventions
No disease group:traditional Chinese medicine
To disease group:traditional Chinese medicine
Have disease group:traditional Chinese medicine
Sponsors
Tongde Hospital of Zhejiang Province
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The standard of "no disease" in TCM for primary liver cancer: Based on the previous diagnosis of primary liver cancer, with reference to stratified Screening and Monitoring Guidelines for Primary Liver Cancer (2020 Edition) and TCM Diagnosis and Treatment Guidelines for Tumor, and combined with the preliminary research of the project team, the "disease-free" criteria for primary liver cancer should be formulated, which should include the following low-risk and medium-risk groups of liver cancer: 1. HBV infection in immune tolerance stage; 2. Antiviral therapy achieves sustained virologic response (SVR) for HBV or HCV-related chronic hepatitis; 3. Normal non-viral liver disease with ALT and platelets; 4. Male, aged 40 years; Female, aged > 50 years; HBV/ HCV-associated chronic hepatitis without antiviral treatment; 4. Liver nodules (1 ~ 2 cm) or low-grade dysplastic nodules (LGDN) or high-grade dysplastic nodules (HGDN) were detected by abdominal ultrasonography; 5. HBV or HCV-related nodules of cirrhosis ( < 1cm); 6. Co-risk factors such as diabetes mellitus or family history of liver cancer in first-degree relatives are associated with HBV or HCV-related cirrhosis who have not received antiviral therapy or LLV after treatment. The standard of "already sick" in TCM for primary liver cancer: Based on the previous diagnosis of primary liver cancer, with reference to the Guidelines for Hierarchical Screening and Monitoring of Primary Liver Cancer (2020 Edition) and The Guidelines for TCM Diagnosis and Treatment of Tumor, and combined with the preliminary research of the project team, the "already sick" criteria for primary liver cancer should be formulated, which should include: 1. Preoperative laboratory and imaging examination was considered as hepatocellular carcinoma; 2. Hepatocellular carcinoma (HCC) was diagnosed by histopathology.
Exclusion criteria
Exclusion criteria: No disease group, To disease group, Have disease group: 1. PST > 2 scores; 2. Patients with serious primary diseases of cardiovascular, liver, kidney and hematopoietic system and mental diseases; 3. Pregnant or lactating women; 4. Persons with disabilities as defined by law; 5. Unwilling to accept research measures, or unable to cooperate for other reasons; 6. Known or suspected allergic history or serious adverse reactions to Traditional Chinese medicine; 7. Participants in other clinical trials within 3 months prior to enrollment; 8. Previous history of malignant tumor; 9. Have high risk factors of liver cancer such as cirrhosis; 10. Accompanied with diseases that may affect tongue and pulse, such as hemangioma, varicose veins of lower limbs, tongue lesions, etc.; 11. Other conditions that the investigator considers inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| alpha-fetoprotein;survival time; | — |
Countries
China
Contacts
Public ContactZhiming Hu
Tongde Hospital of Zhejiang Province
Outcome results
None listed