Normal high blood pressure
Conditions
Interventions
Experimental group:GouTengXuanShen KeLi+ lifestyle intervention
Control group:Placebo + lifestyle intervention
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 - 65 years; 2. It conforms to the western diagnostic standard of normal high value hypertension and TCM syndrome differentiation standard of hyperactivity of liver Yang; 3. No clear history of essential hypertension, and no antihypertensive drugs in the past 3 months; 4. Informed consent and signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary elevated blood pressure; 2. Applicants who have received clinical trials of other new drugs in the last 3 months; 3. Pregnant or trying to get pregnant and breast-feeding women; 4. People who have been allergic to multiple drugs or have an allergic constitution; 5. Persons with combined mental illness, alcoholism and/or psychoactive substance substance abuse and dependence; 6. Excessive daily consumption of tea, coffee or caffeinated beverages; 7.1 Type diabetes, or type 2 diabetes with poor blood glucose control (fasting blood glucose > 11 mmol/L) or complications (kidney disease, peripheral neuropathy); 8. Gastrointestinal diseases or gastrointestinal surgery may affect drug absorption and other serious diseases of the digestive system; 9. Patients with the following organ damage or diseases: cerebrovascular diseases with a history of 12 months (cerebral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis, cerebral infarction and transient ischemic attack); Acute coronary syndrome with a 3-month history; Decompensated heart failure (NYHA grade III ~ IV); Renal insufficiency (creatinine greater than the upper limit of normal); Abnormal liver function (ALT, AST > 1.5 times the upper limit of normal value); Active, recurrent ulcers of the digestive system or other diseases at risk of bleeding; Complicated with malignant tumor, hematologic disease or other systemic serious or progressive disease.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The score of TCM syndrome;Duchenne revised hypertension quality of life scale;Blood fat;Blood sugar;Urinary microalbumin;Blood uric acid;Blood homocysteine;Hypersensitive C-reactive protein; | — |
Primary
| Measure | Time frame |
|---|---|
| Blood pressure; | — |
Countries
China
Contacts
Public ContactYunlun Li
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed