gout
Conditions
Interventions
Sponsors
Shanghai Tenth People's Hospital, Tongji University
Eligibility
Sex/Gender
All
Age
19 Years to 65 Years
Inclusion criteria
Inclusion criteria: Gout group: 1. Patients diagnosed with gout according to the 2015 ACR/EULAR gout classification criteria; 2. Aged > 18 years; 3. In accordance with the American College of Rheumatology guidelines for Gout Treatment 2020, Treatment indications of ULT: Start ULT for patients with any of the following conditions: >= 1 subcutaneous tophi; Radiographic injury due to gout (in any form); The frequency of gout was defined as >= 2 times/year. Hyperuricemia group: 1. Blood uric acid level exceeded 420 µmol/L twice on different days. 2. Asymptomatic HUA patients can start uric-lowering drug therapy when the following conditions occur: blood uric acid level >= 540 µmol/L or blood uric acid level >= 480 µmol/L and one of the following complications: hypertension, abnormal lipid metabolism, diabetes, obesity, stroke, coronary heart disease, cardiac insufficiency, uric acid nephrolithiasis, renal impairment (CKD stage 2 and above).
Exclusion criteria
Exclusion criteria: 1. Patients who did not adhere to ULT as required; 2. Patients with other bone and joint diseases, including osteoarthritis, rheumatoid arthritis or psoriatic arthritis, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood uric acid value;Double contour sign;tophus;bony erosion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Synovial membrane thickness;Synovial blood flow; | — |
Countries
China
Contacts
Public ContactHui Zhao
Shanghai Tenth People's Hospital, Tongji University
Outcome results
None listed