Multidrug-resistant bacterial pneumonia
Conditions
Interventions
Treatment group:Oral traditional Chinese medicine + related antibiotic mimicks
Control group:Related antibiotics + oral Chinese medicine mimicks
Sponsors
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for community-acquired pneumonia or hospital-acquired pneumonia, and the airway secretions are cultured as multidrug-resistant Gram-negative bacilli; 2. Aged >= 18 years; 3. Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Acute organ function injuries >= 2; 3. Acute physiological function and chronic health status score II (APACHEII) >= 25 points; 4. Allergic or intolerant to the drugs used in this test; 5. Patients with serious primary diseases such as heart, liver, kidney and hematopoietic system, advanced malignant tumors, poor control of diabetic blood glucose, and patients with mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| case fatality rate;Sputum bacterial clearance ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Lung Infection Score (CPIS) ;White Blood Cell;C-Reactive Protein;procalcitonin;interleukin-6;tumor necrosis factor-a; | — |
Countries
China
Contacts
Public ContactXin Zhao
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed