Knee osteoarthritis
Conditions
Interventions
Traditional Chinese medicine group:Take Juanbi Qianggu Formula
Western medicine group:Take celecoxib
Sponsors
Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Agree to participate in this study and sign the informed consent form; 2.Meet the diagnostic criteria of osteoarthritis stipulated by the classification standard of American rheumatic association (ACR) in 1995; meet the standard for differentiation of symptoms and signs of "liver and kidney deficiency" bone arthralgia syndrome in traditional Chinese Medicine in Diagnosis and treatment guide for osteoarthritis (2018 Edition) and Chen Weiheng Guidelines for diagnosis and treatment of knee osteoarthritis in traditional Chinese medicine (2020 Edition); 3.KL level 6.
Exclusion criteria
Exclusion criteria: 1. Abnormal liver and kidney function; 2. Pregnant or lactating women, psychopaths; 3. Patients with serious diseases such as heart, liver, brain, kidney and hematopoietic system; 4. Severe overlapping rheumatoid arthritis; 5. Late stage patients, severe joint deformity; 6. Those who received other investigational drugs 3 months before screening; 7. Unable or unwilling to comply with test requirements; 8. All subjects considered unsuitable by the investigator for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Arthritis Index;Numerical rating scale;American knee society score;Hamilton Depression Scale Scale;Imaging examination; | — |
Countries
China
Contacts
Public ContactXu Bo
Shanghai University of Traditional Chinese Medicine
Outcome results
None listed