spinocerebellar ataxia
Conditions
Interventions
Experimental group 1:real-intermittent theta burst stimulation
Experimental group 2:sham-intermittent theta burst stimulation
Sponsors
Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Ataxia symptoms; 3. Family history, confirmed as SCA by genetic testing; 4. Signed informed consent; 5. SARA score greater than 3 points.
Exclusion criteria
Exclusion criteria: 1. Those with metal foreign bodies in the skull, those with brain tumors, brain trauma, or brain surgery; 2. Those with cardiac pacemakers, cardiac stents, or cochlear implants; 3. History of epilepsy or EEG Abnormalities; 4. Critically ill patients with unstable vital signs and those who do not cooperate; 5. Severe nervous system diseases; 6. Patients taking drugs that affect metabolism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transcranial magnetic stimulation-electroencephalography;Transcranial magnetic stimulation-electromyography;Ataxia Scale;serum neurofilament light chain; | — |
Secondary
| Measure | Time frame |
|---|---|
| non-ataxia scale; | — |
Countries
China
Contacts
Public ContactZhongming Gao
Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed