Lung protection ventilation strategy
Conditions
Interventions
Test group:Start low tidal volume ventilation with 6mL/kg
control group:Start conventional tidal volume ventilation with 10mL/kg
Sponsors
Taizhou People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. American Society of anesthesiologists (ASA) grade I ~ III; 2. Aged >= 18 years; 3. The estimated operation time is more than 120 min; 4. Sinus rhythm; 5. BMI is 18-30 kg/m2;
Exclusion criteria
Exclusion criteria: 1. The patient refused to participate in the study and did not sign the informed consent form; 2. Serious lung diseases, such as chronic obstructive pulmonary disease, pleural effusion, asthma, pneumothorax, previous chest surgery history, such as lobectomy; 3. Serious arrhythmia, cardiovascular disease, liver and kidney dysfunction, etc; 4. Patients whose skin or chest diseases make transthoracic echocardiography infeasible; 5. Patients with previous history of gastro colorectal surgery, cardiac surgery or chemotherapy for gastro colorectal cancer; 6. Preoperative oxygen saturation <= 90%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular myocardial performance index;Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Artery Pressure;lactic acid;PaCO2;creatine phosphate kinase;creatine phosphate kinase-MB;lactic dehydrogenase; | — |
Countries
China
Contacts
Public ContactLin Jiang
Taizhou People's Hospital
Outcome results
None listed