coronary atherosclerotic heart disease
Conditions
Interventions
DES group:Drug-eluting stents
Sponsors
Fuwai Central China Cardiovascular Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40 - 75 years; 2. Patients clinically diagnosed as coronary atherosclerotic heart disease, coronary angiography showed that PCI was needed, OCT confirmed that lesion is coronary artery intimal calcification, OCT score >= 2, and the lesion after pre-treatment is suitable for drug-eluting stent and drug-coated balloon. 3. For patients with diabetes and hypertension, blood sugar and blood pressure were up to standard before operation; 4. Patients and their families signed the informed consent, and were willing to cooperate with the follow-up until 12 months after operation.
Exclusion criteria
Exclusion criteria: 1. NYHA > III, or left ventricular ejection fraction < 30%; 2. In-stent restenosis after coronary artery bypass grafting or PCI; 3. Patients with muscular bridge, severe angular lesions, extensive thrombosis in the diseased vessels, and severe valvular heart disease requiring surgical treatment; 4. Patients who can't tolerate dual antiplatelet therapy, antiplatelet therapy and/or anticoagulation therapy contraindicated; 5. Patients with severe organ dysfunction, autoimmune diseases, malignant tumors, or expected survival time <= 3 years; 6. Pregnant women, patients with iodine contrast agent, paclitaxel, rapamycin allergy or contraindication of interventional therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Late lumen loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Target Lesion Revascularizition;major adverse cardiac events; | — |
Countries
China
Contacts
Public ContactYang Honghui
Fuwai Central China Cardiovascular Hospital
Outcome results
None listed