hemiplegia after cerebral infarction
Conditions
Interventions
Test group:Acupuncture at Yanglingquan
Healthy control group:Acupuncture at Yanglingquan
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: Hemiplegia patients test group: 1. Patients with cerebral infarction whose course of disease is 1.5 months conform to the diagnostic criteria of cerebral infarction (Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2014); 2. Right-handed; 3. Aged 40 - 75 years, both men and women are eligible; 4. In patients with left hemiplegia, the infarct was located in the right basal ganglia and/or the radiation coronal region; 5. The patient has unconscious disorder and the condition is relatively stable; 6. No psychotropic drugs have been taken in the past month; 7. Here is no metal in the body and no contraindication of nuclear magnetic resonance examination; 8. The patient himself or his immediate family members sign the informed consent. Healthy subjects group: 1. Right-handed; 2. Aged 40 - 75 years, both men and women are eligible; 3. Those who have been proved to be in the range of physical health by physical examination have no organic or significant functional diseases; 4. No family genetic history of mental and nervous system; 5. No research similar to this experiment has been conducted; 6. There were no physical abnormalities (such as cold, headache, cough, etc.) during the experimental period; 7. No excitatory drugs have been taken in the past two months; 8. There are no metal implants in vivo and no contraindications for functional magnetic resonance imaging. 9. Subjects signed the informed consent and volunteered to participate in the experiment.
Exclusion criteria
Exclusion criteria: Hemiplegia patients test group: 1. Combining with psychiatric disorders or any other serious primary diseases; 2. Being pregnant, lactating or menstrual; 3. Severe skull anatomical asymmetry or definite lesions being found by MRI scans; 4. Taking part in similar neuroimaging test within 1 month. Healthy subjects group: 1. Being menstrual, pregnant or lactating; 2. Severe skull anatomical asymmetry or definite lesions being found by MRI scans.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Granger analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment;National Institutes of Health Stroke Scale;Needle Sensation Assessment Scale;Fractional anisotropy (FA);Modified Ashworth scale;Hamilton Depression Scale (HAMD);Brunnstrom Scale;Mini-Mental State Examination (MMSE);Motricity Index;Barthel Index; | — |
Countries
China
Contacts
Public ContactYihuai Zou
Dongzhimen Hospital, Beijing University of Chinese Medicine
Outcome results
None listed