Obesity, type 2 diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 30 - 45 years, regardless of gender; 2. Diagnosed type 2 diabetes mellitus with HbA1c of 6.0-7.5%. Untreated with hypoglycemic drugs in the past 3 months, and has no intention to add hypoglycemic drugs at present; 3. Body mass index (BMI) >= 28 kg/m2, or waist circumference greater than 90 cm for men and 85 cm for women.
Exclusion criteria
Exclusion criteria: 1. History of chronic renal insufficiency, glomerular filtration rate 2 times of the normal upper limit; 3. Organ failure (heart failure, respiratory failure, etc.), history of malignant tumor, acute and chronic infectious diseases; 4. 40 grams of alcohol per day for men and 24 grams per day for women; 5. Patients who are participating in other clinical trials; 6. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visceral and subcutaneous fat area, liver fat volume, and brown adipose tissue activity in the neck;Blood biochemical index;Anthropometric index;Intestinal flora index; | — |
Countries
China
Contacts
Ji'nan Central Hospital