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A multi-center study: the application value of plasma exosomal non-coding RNA in the early screening and clinical progress of colorectal cancer

Identification and evaluation of circulating exosome microRNA as diagnostic biomarkers for patients with colorectal tumors and monitoring the clinical progression of colorectal cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061592
Enrollment
Unknown
Registered
2022-06-29
Start date
2022-06-15
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenomas and colorectal cancer

Interventions

RT-qPCR&#32
Gold Standard:Gastroscopy, colonoscopy, pathological diagnosis
extraction:&#32
commercial&#32
kit&#32
(EZB&#32
company)&#32
extraction. Extraction&#32
of&#32
miRNA:&#32

Sponsors

Changzheng Hospital, Naval Medical University (Second Military Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 20-80 years old; 2. Karnofsky score >= 80; 3. Gastroscopy was performed within 3 months, and no obvious organic lesions (including malignant lesions, polyps and ulcers) were found; 4. Patients and their families Able to understand the research protocol and willing to participate in this research, provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. ASA IV to V; 2. Pregnant or breastfeeding women; 3. Severe cardiovascular disease, uncontrolled infection, or other uncontrolled comorbidities; 4. Combined with a history of other multiple tumor diseases, or combined with other genetic diseases; 5. The patients or their families cannot understand the conditions and objectives of this study.

Design outcomes

Primary

MeasureTime frame
exosome microRNA;

Countries

China

Contacts

Public ContactZhiqian Hu

Changzheng Hospital, Naval Medical University (Second Military Medical University)

huzhiq163@163.com+86 13801790599

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026