Breast cancer
Conditions
Interventions
Control group:Opioid based general anesthesia
Observation group:Opioid free general anesthesia
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
Female
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Those who plan to carry out unilateral breast cancer radical mastectomy; 2. Agree to participate in the study and sign the informed consent form; 3. Age 35-75 years old; 4. ASA class I or II; 5. BMI18-25kg/m2.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to nerve block (coagulation system disease, infection of the puncture site, etc.); 2. Patients with chronic pain or long-term use of analgesic drugs; 3. Patients who are allergic to the drugs used in the study; 4. Patients with mental illness or inability to cooperate; 5. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40 (40 recovery quality rating scale); | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical rating scale, NRS;Incidence of postoperative nausea and vomiting;Richmond Agitation-Sedation Scale, RASS;Consumption of intraoperative sedative and analgesic drugs;Dosage of relief analgesics;Adverse reactions occurred during perioperative period; | — |
Countries
China
Contacts
Public ContactWenping Ding
Xuzhou Central Hospital
Outcome results
None listed