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A clinical observation of ciprofol, propofol and etomidate on hemodynamic imaging during induction period of general anaesthesia in patients with hypertension

A clinical observation of ciprofol, propofol and etomidate on hemodynamic imaging during induction period of general anaesthesia in patients with hypertension

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061579
Enrollment
Unknown
Registered
2022-06-29
Start date
2023-04-01
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective surgery

Interventions

Ciprofo:Intravenous titration of Ciprofo 0.4mg/kg
Propofo:Intravenous titration of Propofo 2.0mg/kg
Etomidate:Intravenous titration of Etomidate 0.3mg/kg

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 60 years; 2. ASA grades I~III; 3. Diagnosed as essential hypertension 4.Patients undergoing elective surgery under general anesthesia; 4. Respondents agreed to participate in the study and signed the informed consent form; 5. The patience with hypertension.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to ciprofol, propofol injection components and other anesthetics; 2. Patients with neurological symptoms such as cerebrovascular disease, previous cerebral infarction, and epilepsy; 3. Pregnant and lactating women; 4. The patience with difficult airway; 5. Patients with obvious respiratory dysfunction like OSAS, Acute Respiratory Infections, and so on; 6. Patients with obvious circulatory dysfunction; 7. Resting ECG heart rate <50r/min, III atrioventricular block.

Design outcomes

Secondary

MeasureTime frame
Blood pressere;Mean arterial pressure;Incidence of perioperative adverse effects;Heart rate;Use of Ephedrine Hydrochloride Injection;

Primary

MeasureTime frame
Incidence of post-induction hypotension;

Countries

China

Contacts

Public ContactZou Xiaohua

Affiliated Hospital of Guizhou Medical University

562931613@qq.com+86 138 0941 6063

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026