A Mechanical Study on Virtual Reality for Neuromodulation of Chronic Pain based on Multimodal Analysis of Brain Network

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200061536

Enrollment

Unknown

Registered

2022-06-28

Start date

2022-11-01

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pain

Interventions

Experimental group 1:rTMS+VR

Experimental group 2:rTMS

Healthy control group:No intervention

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. 25-50 years old; 2. Male or female; 3. Complain of pain at any site in trunk or lower extremities, with symptoms sustained at least 3 months or above, with clinical evidence and neuroimaging evidence supported; 4. At least 4 scores or above by VAS self-rating scale.

Exclusion criteria

Exclusion criteria: 1. Pain at any site over upper extremities; 2. Comorbidities include one or more of the following items; Diabetes, cardiovascular disorders, rheumatoid arthritis, gout, cervical neuropathy, spinal cord injuries or central/peripheral nervous system disorders or cancer; 3. Motion sickness; 4. Surgical or traumatized history at head or pain site; 5. Associated with majory systematic disorders or MRI contraindications, including pace maker, metal implants, pregnancy, claustrophobia.

Design outcomes

Primary

Measure	Time frame
Beta value;Featured value;Functional connectivity;	—

Countries

China

Contacts

Public ContactDeng Xue

The 8th Affiliated Hospital of Sun Yat-Sen University (Shenzhen Futian)

eux952@qq.com+86 13537650287

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026