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Application of breath VOC biomarkers in differentiating malignan from benign early pulmonary nodules

Application of breath VOC biomarkers in differentiating malignan from benign early pulmonary nodules

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061519
Enrollment
Unknown
Registered
2022-06-27
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 20-80, male or female; 2. Pulmonary nodules were detected by low-dose spiral CT, chest CT or high-resolution thin-layer CT; 3. The maximum diameter of pulmonary nodules ranged from 5 to 30mm; 4. Three imaging types of pulmonary nodules can be grouped, solid nodule (SN), nonsolid nodule (NSN/GGO), and partial solid nodule (PSN); 5. The patient needed pulmonary nodule resection to determine the nature of the nodule; 6. The patient must be able to fully understand the informed consent form and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. The pathological diagnosis of pulmonary nodules could not be confirmed after surgical resection or biopsy; 2. The patient was previously diagnosed with malignant tumor (except for cured non malignant and pigmented

Design outcomes

Primary

MeasureTime frame
Exhaled volatile organic compounds (VOC) molecules in the exhalation;

Countries

China

Contacts

Public ContactLi Lei

West China Hospital, Sichuan University

lileililei41@163.com+86 15608030047

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026