Peripheral neuropathy caused by chemotherapy for malignant tumor
Conditions
Interventions
Experimental group:Warm needle
Control group:Mecobalamin dispersible tablet
Sponsors
Chongqing Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Malignant tumor was confirmed by pathology and treated with albumin-bound paclitaxel combined with cisplatin Treatment (albumin-bound paclitaxel 260mg/m2 + 100mg/m2 cisplatin); 2. 18-75 years old; 3. Karnofsky score >=80; 4. Before chemotherapy, routine blood tests, liver and kidney functions, and electrocardiogram were normal; 5. No positive signs were found in the neurological examination; 6. The expected survival time is >3 months; 7. Consistent with the clinical manifestations of TCM blood bi syndrome; 8. The subject agrees and signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. patients with pre-existing neurological diseases; 2. Suffering from mental disorders or unable to cooperate; 3. patients with diabetes who may cause peripheral paresthesia; (4) patients receiving other chemotherapy drugs that may cause neurotoxicity; (5) Symptoms of nerve compression due to brain metastasis or limb metastasis;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nerve conduction studies;Brief Pain Inventory, BPI;CIPN neurotoxicity occurrence and grading criteria;TCM symptom rating table; | — |
Countries
China
Contacts
Public ContactSong Na
Chongqing Traditional Chinese Medicine Hospital
Outcome results
None listed