Postoperative nausea and vomiting
Conditions
Interventions
Group A:OFA in the first operation and OBA in the second operation
Group B:OBA in the first operation and OFA in the second operation
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. American Society of Anesthesiologists (ASA) physical status I-III; 3. Scheduled for at least two surgical procedures for wound treatment under general anesthesia (interval between two procedures at least 5 days).
Exclusion criteria
Exclusion criteria: 1. Unplanned or emergency surgery; 2. Left ventricular ejection fraction < 40%, second-degree or greater atrioventricular block, sick sinus syndrome, or severe bradycardia (heart rate < 50 beats/min); 3. Serious liver or renal dysfunction (Child-Pugh grade C or renal replacement therapy); 4. Epilepsy or seizures; 5. Preoperative use of sedatives and analgesics; 6. Allergy to medications used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting (PONV); | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of PONV (Incidence of postoperative nausea and vomiting);Antiemetic rescue therapy;Pain scores;Worst pain;Need for rescue analgesia;Postoperative sedation;hypotension;Bradycardia;Hypertension;Tachycardia;Hypoxemia;Length of PACU stay;Time to extubation;Psychotomimetic or dissociative effects; | — |
Countries
China
Contacts
Public ContactPeng Ke
The First Affiliated Hospital of Soochow University
Outcome results
None listed