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Clinical data analysis of bevacizumab-induced hypertension in patients with colorectal cancer

Clinical data analysis of bevacizumab-induced hypertension in patients with colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061510
Enrollment
Unknown
Registered
2022-06-27
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

None:None

Sponsors

The Sixth Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 82 Years

Inclusion criteria

Inclusion criteria: 1. The patient was diagnosed with metastatic colorectal cancer and had no other tumors; 2. The patient was receiving bevacizumab in combination with other chemotherapy drugs; 3. The patient had not received VEGF inhibitor treatment before; 4. The patient used at least 3 courses of bevacizumab.

Exclusion criteria

Exclusion criteria: 1. With other tumors at the same time; 2. With other uncontrollable systemic diseases; 3. Previously treated with other VEGF inhibitors; 4. Patients received bevacizumab less frequently 3 times.

Design outcomes

Primary

MeasureTime frame
Blood pressure;Overall survival;Progress-free survival;Blood pressure from 2 months before treatment to 6 months after treatment, or before treatment with other VEGF inhibitors and other pressors;The use of bevacizumab, atropine, irinotecan and antihypertensive drugs;

Countries

China

Contacts

Public ContactZhuoling Zheng

The Sixth Affiliated Hospital of Sun Yat-Sen University

zhengzhling@mail.sysu.edu.cn+86 13824471579

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026