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A single-center, randomized, double-blind, placebo-controlled clinical study of efficacy and safety of Suhuang Cough capsule in the treatment of cough symptoms in patients with acute exacerbation of chronic obstructive pulmonary disease

A single-center, randomized, double-blind, placebo-controlled clinical study of efficacy and safety of Suhuang Cough capsule in the treatment of cough symptoms in patients with acute exacerbation of chronic obstructive pulmonary disease

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061495
Enrollment
Unknown
Registered
2022-06-27
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Group 1:Suhuang cough capsule + conventional treatment
Group 2:Placebo+conventional treatment

Sponsors

The First Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. Meet the diagnostic criteria for acute exacerbation of chronic obstructive pulmonary disease; 3. The informed consent process complies with the regulations, and the informed consent is signed; 4. Cough VAS score >=40 points.

Exclusion criteria

Exclusion criteria: 1. Patients with serious heart, liver, kidney, brain, mental, neurological disorders and patients with any tumor; 2. Pregnant or lactating patients or those planning to become pregnant; 3. Known allergy to study drug or drug composition.

Design outcomes

Primary

MeasureTime frame
Visual analog score improvement rate;

Secondary

MeasureTime frame
Rate of improvement on the Lycester cough quality of life questionnaire (LCQ) score;Improvement rate of COPD patient self-assessment test (CAT) questionnaire score;Improvement rate of patient dyspnea evaluation scale (mMRC) score;

Countries

China

Contacts

Public ContactChen Ruchong

The First Affiliated Hospital of Guangzhou Medical University

chen_rch@163.com+86 13710723826

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026