Hypertension and tachycardia caused by esketamine
Conditions
Interventions
Control group:None
Intervention group:Esmolol 0.5 mg/kg administrated intravenously for 30 seconds after a dose of esketamine
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
Male
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. Healthy children aged 3–7 years who underwent circumcision. 2. Written informed consent was obtained from the parents or legal guardians of the children.
Exclusion criteria
Exclusion criteria: 1. Allergic to Esketamine. 2. Dysfunction of liver and kidney. 3. History of asthma. 4. ASA grade >=2. 5. Other systemic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs (Noninvasive blood pressure, heart rate, pulse oxygen saturation); | — |
Countries
China
Contacts
Public ContactLi Bo
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed