None listed
Conditions
Interventions
Propofol group:propofol
Sponsors
Minhang Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=65 and =10 and =95% when breathing air; Systolic blood pressure (SBP) >=90mmHg and =60mmHg and =55 and <=100 beats/min; 8. No serious medical disease; 9. Be able to understand the research process and methods, and voluntarily participate in the research.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to general anesthesia or previous history of anesthesia accidents; 2. Known or suspected allergy or contraindication to propofol, cyclopofol excipients, benzodiazepines, opiates, muscle relaxants, etc.; 3. Patients complicated with craniocerebral loss, intracranial hypertension, stroke, unstable angina pectoris, myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, presence of a difficult airway, or determination of difficulty intubating the trachea (modified Markov score Level III or IV); 5. Uncontrolled diabetes or hypertension; 6. Severe liver dysfunction or severe renal insufficiency; 7. History of alcoholism or drug dependence; 8. Abuse or long-term use of narcotic, sedative and analgesic drugs; 9. Previous history of mental illness; 10. Participated in any drug clinical trials within 1 month prior to screening; 11. The reluctance of fertile women or men to use contraception throughout the trial period; Patients (including male subjects) who plan to become pregnant within 1 month after the trial; 12. Patients with any other factors deemed unsuitable for participation in this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean arterial pressure; | — |
Countries
China
Contacts
Public ContactZhang Nu
Outcome results
None listed