Stroke
Conditions
Interventions
Acupuncture Comprehensive Program Group:Acupuncture + rehabilitation therapy + basic Western medicine therapy
Healthy Group:None
Sponsors
Shenzhen Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for patients with ischemic stroke: (1) Meet the diagnostic criteria for ischemic stroke; (2) The clinical stages of ischemic stroke were convalescent stage and sequelae stage; (3) Unilateral limb movement disorders, including upper limb or lower limb movement disorders, without ataxia; (4) Clear consciousness, can cooperate with the completion of scale evaluation, magnetic resonance examination and acupuncture comprehensive treatment; (5) Aged 45-80 years, no gender limit; (6) The subjects with ischemic stroke were mild or moderate, i.e. the NIHSS score was within the range of 1-20 points; (7) Normal cognitive function, MMSE>=18 points (uneducated), 20 points (primary education or above), 24 points (secondary education or above). 2. Inclusion criteria of healthy subjects: (1) Aged 45-80 years, primary school education or above, no gender limit; (2) Han nationality, right-handed; (3) Generally feel healthy and have no history of mental disease or nervous system disease; (4) No other MRI contraindications such as claustrophobia; (5) Normal cognitive function, MMSE>=18 points (uneducated), 20 points (primary school or above culture), 24 points (middle school or above culture); (6) Participate in the experiment voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for subjects with ischemic stroke: (1) The present disease is accompanied by intracranial infection, intracranial hypertension, severe cerebral edema, continuous deterioration of neurological function, frequent epilepsy; (2) The patient is accompanied by severe cardiopulmonary insufficiency, atrial fibrillation, pulmonary infection, gastrointestinal bleeding, tumor, liver and renal failure, etc.; (3) Patients with intracranial infection, brain demyelinating diseases, and mental and psychological diseases; (4) Patients with previous or current disease and history of craniocerebral trauma, intracranial tumors, and craniotomy. 2. Exclusion criteria for healthy subjects: (1) A history of stroke, brain tumor, Parkinson's disease, encephalitis, epilepsy, and brain trauma; (2) Patients with serious mental illness, alcohol, drugs or other psychotropic drug abusers; (3) Patients with severe hearing and vision impairment and aphasia who cannot achieve the assessment and cannot complete the study; (4) Patients with a history of severe head trauma or other diseases involving the central nervous system; (5) Patients with serious systemic diseases such as heart, liver and kidney insufficiency; (6) Others considered unsuitable for inclusion by the researcher.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Barthel Index;Modified Rankin Scale;Cortical thickness;Fugl-Meyer score;Functional connection;Mean diffusion kurtosis;Fractional anisotropy;Blood flow; | — |
Countries
China
Contacts
Public ContactGong Mingqiang
Shenzhen Hospital of Traditional Chinese Medicine
Outcome results
None listed