None listed
Conditions
Interventions
Sponsors
Shengjing Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged >=65 years; 2. Voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe hearing and visual impairment, unable to read; 2. Patients with severe consciousness disorder or inability to communicate (coma, deep dementia or language disorder) or MMSE score <20 or cognitive dysfunction before surgery; 3. Preoperative psychiatric diseases (schizophrenia, mania, bipolar disorder, insanity, etc.); 4. Preoperative history of epilepsy, Parkinson's syndrome or myasthenia gravis; 5. Known preoperative left ventricular ejection fraction of less than 30%, pathological sinus syndrome, severe sinus bradycardia (< 50 beats/min), or second degree or larger atrioventricular block without pacemaker; 6. Severe liver dysfunction (Child-Pugh grade C); 7. Severe renal insufficiency (dialysis prior to surgery); 8. Patients expected to be admitted to ICU after surgery; 9. Patients with known allergy to the active ingredient of sodium oxybutyrate injection, or contraindications to sodium oxybutyrate use such as hypokalemia, ethanol intoxication, and severe cardiac insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Confusion Assessment Method; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination; | — |
Countries
China
Contacts
Public ContactZhao Ping
Outcome results
None listed