Skip to content

Clinical observation of alfentanil combined with propofol in hysteroscopic surgery

Clinical observation of alfentanil combined with propofol in day surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061458
Enrollment
Unknown
Registered
2022-06-25
Start date
2022-06-12
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group:Intravenous fentanyl 10µg/kg
Control group 1:Intravenous butorphanol 20µg/kg
Control group 2:Intravenous sufentanil 0.1ug/kg

Sponsors

Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Women who intend to undergo hysteroscopic surgery; 2. Aged 18-55 years; 3. American Society of Anesthesiologists (ASA) grade I to II.

Exclusion criteria

Exclusion criteria: 1. Patients who refused to participate in the trial; 2. Patients with a history of serious heart, brain, lung, liver, kidney and metabolic diseases; 3. Patients with a history of recovery from abnormal surgical anesthesia; 4. Electrocardiogram: heart rate 180mmHg and/or diastolic blood pressure >110mmHg in hypertensive patients, or <90/60mmHg in hypotensive patients; 7. Patients with neuromuscular system diseases and mental diseases; 8. Anemia patients; 9. Suspected abuse of narcotic analgesics or sedatives; 10. Those who predict that difficult airway may occur or have occurred before; 11. Known allergy to emulsions and opiates; 12. Uncooperative and unable to communicate.

Design outcomes

Primary

MeasureTime frame
Body movement response times;Propofol total dosage;Time to reach a score of 5 on the modified Vigilance/Sedation Scale (MOAA/S);Pulse oxygen saturation in PACU;

Countries

China

Contacts

Public ContactYuan Hongmei

Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital

yuanhm667@126.com+86 13851489532

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026