sepsis
Conditions
Interventions
The groups were divided into death and non-death groups, shock and non-shock groups according to prognosis, and PD-1 high expression group and low expression group of Treg according to experimental re
Sponsors
Guangdong Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of sepsis 3.0; (2) the time of onset is less than 7 days.
Exclusion criteria
Exclusion criteria: (1) Patients less than 18 years old; (2) Patients who are unable to defecate for various reasons; (3) End-stage chronic diseases such as malignant tumors, the estimated survival time is less than 28 days; (4) Patients with autoimmune diseases, immune deficiencies or long-term use of immunosuppressants; (5) Pregnant women; (6) Patients and their families do not agree to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| survival on 28 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bacterial flora 16 S rDNA sequencing;Peripheral blood Treg, CD4 +T cells, CD8 +T cells and NK cells co-signaling molecule expression assay; | — |
Countries
China
Contacts
Public ContactWenqiang Jiang
Guangdong Provincial People's Hospital
Outcome results
None listed