sudden hearing loss
Conditions
Interventions
Treatment effective group:Intratympanic injection combined with systemic corticosteroids
Treatment ineffective group:Intratympanic injection combined with systemic corticosteroids
Sponsors
The Second Affiliated Hospital of PLA Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 84 Years
Inclusion criteria
Inclusion criteria: 1) Age 18~84 years old 2) Patients with unilateral sudden deafness greater than 30 dB occurring on at least three consecutive frequencies for unknown reasons within 72 hours
Exclusion criteria
Exclusion criteria: 1) Middle ear lesions, retrocochlear mass, Meniere's disease, and large vestibular aqueduct syndrome; 2) Genetic factors and other pathogenic factors; 3) Pregnant women and those with contraindications to glucocorticoid use; 4) Medical records Incomplete information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pure tone hearing threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| White blood cell count;age;BMI;Hypertension;Triglyceride;Total Cholesterol;High Density Lipoprotein-Cholesterol;Low Density Lipoprotein-Cholesterol;Fasting Plasma Glucose;Absolute Neutrophil Count;Lymphocyte count;neutrophil to lymphocyte ratio(NLR);monocyte;red blood cell count;platelet count(PLT);platelet to lymphocyte ratio(PLR);activated partial thromboplastin time(APTT);fibrinogen dissolution products(FDP);fibrinogen(Fib);incentive;location;tinnitus;Aural fullness;vertigo;course; | — |
Countries
China
Contacts
Public ContactLian-Jun Lu
Outcome results
None listed