Dexamethasone for Prophylaxis of Postoperative Nausea and Vomiting in Mastectomy: a Non-inferiority Randomized Controlled trial

Transcutaneous Electrical Acupoint Stimulation versus Dexamethasone for Prophylaxis of Postoperative Nausea and Vomiting in Mastectomy: a Non-inferiority Randomized Controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200061377

Enrollment

Unknown

Registered

2022-06-22

Start date

2022-06-30

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Electrical stimulation group:PC6 Transcutaneous Electrical Acupoint Stimulation

Dexamethasone group:Dexamethasone 8mg

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.Elective lumpectomy 2.18-75 years old, female 3.ASA classification I-III

Exclusion criteria

Exclusion criteria: 1. Have received acupuncture within 2 weeks; 2. Suffering from the central nervous system or psychiatric disorders; 3. Diabetes; 4. Patients who are not suitable for transcutaneous electrical acupoint stimulation, such as those with damaged skin at the stimulation site, abnormal coagulation function, and bleeding tendency.

Design outcomes

Primary

Measure	Time frame
Incidence of nausea and vomiting within 24 hours after surgery;	—

Secondary

Measure	Time frame
Severity of nausea and vomiting within 24 hours of surgery;Number and dose of rescue antiemetics;Satisfaction score;Incidence of adverse events;Feasibility of automatic control technology scheme of PC6 point stimulation;	—

Countries

China

Contacts

Public ContactYongyan Zhang

331679373@qq.com+86 13127773560

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026