Bipolar disorder
Conditions
Interventions
Study group:Acupuncture therapy
Control group:Sham acupuncture stimulation
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Meet the diagnostic criteria of bipolar depression; ? Gender is not limited and the age is between 18-60 years old; right-handed; ? HAMD-24 scale score =20 points; ? Those who have not taken psychotropic drugs, or psychotropic drugs have been cleaned for one week as required, or have been on cross-drug for one week; ? No metal in the body, no claustrophobia or other contraindications for MRI; ? Voluntary participation in clinical research and sign the informed consent by themselves and/or their guardians.
Exclusion criteria
Exclusion criteria: ? Mental disorders caused by organic brain diseases, or comorbidity of mental disorders related to psychoactive substances, or comorbidity of other types of mental disorders; ? Severe asymmetry of the anatomical structure of the head, or definite lesions are found in the MRI scan; ? Those who have aggressive behavior and strong suicidal tendencies; ? Those with severe physical disease or severe liver and kidney dysfunction; ? Those who experienced obvious discomfort such as fainting during acupuncture treatment; ? Pregnant or lactating women; ? Those who have participated in similar neuroimaging trials within one month; ? Those who received non-convulsive electroconvulsive therapy in the past one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-24 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMA score;Clinical Global Impression Scale score;Side Effects Scale score; | — |
Countries
China
Contacts
Public ContactPei Chen
Outcome results
None listed