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Correlation between perioperative myocardial insulin resistance and postoperative left ventricular dysfunction in patients undergoing cardiopulmonary bypass

Correlation between perioperative myocardial insulin resistance and postoperative left ventricular dysfunction in patients undergoing cardiopulmonary bypass

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061368
Enrollment
Unknown
Registered
2022-06-22
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart disease

Interventions

Cardiopulmonary bypass group:Nil

Sponsors

Chengdu Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Age >18 years old; (2) Obtain the informed consent of the patient or the authorized person before the operation; (3) Patients undergoing open heart surgery under cardiopulmonary bypass.

Exclusion criteria

Exclusion criteria: (1) Patients without cardiopulmonary bypass; (2) patients with diabetes (random blood glucose>=11.1mmol/l or fasting blood glucose>=7.0mmol/l or HbA1c>=6.5%); (3) patients with liver and kidney dysfunction (blood creatinine is 2 times higher than the upper limit of the normal value, aspartate aminotransferase or alanine aminotransferase is 2 times higher than the upper limit of the normal value); (4) heart failure (left ventricular ejection fraction <30%); (5) those who cannot complete the test or have incomplete data; (6) Patients with recent cardiovascular and cerebrovascular accidents before operation (new myocardial infarction within 6 months, new stroke within 6 weeks); (7) patients with other types of endocrine diseases (Cushing's syndrome, acromegaly, pheochromocytoma, glucagon tumor, etc.).

Design outcomes

Primary

MeasureTime frame
insulin;blood glucose;

Countries

China

Contacts

Public ContactYan Yifan
yanyifan183@163.com+86 18337199750

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026