Degenerative knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of knee osteoarthritis; (2) VAS score = 4 points; (3) Disease onset; (4) 40 = age = 75; (5) No drugs affecting the efficacy were used 2 weeks before treatment; (6) Normal mental state and understanding ability; (7) Informed consent of patients and their families, and sign the informed consent form; (8) Approved by the hospital ethics committee.
Exclusion criteria
Exclusion criteria: (1) Patients with knee joint tumor, rheumatoid, tuberculosis, suppuration and acute injury; (2) Suffering from severe skin diseases such as eczema or local skin damage of knee joint; (3) Patients with severe cardiovascular disease or severe liver and kidney insufficiency; (4) Pregnant and lactating women. Note: patients who meet any of the above conditions shall be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Western Ontario and McMaster Universities Osteoarthritis index;Interleukin-1(IL-1);Interleukin-6(IL-6);matrix metalloproteinases-3(MMP-3);matrix metalloproteinases-13(MMP-13); | — |
Countries
China