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A randomized, single-blind, controlled study of remimazolam besylate versus propofol in outpatient facial plastic surgery

A randomized, single-blind, controlled study of rimazolam besylate versus propofol in outpatient facial plastic surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061342
Enrollment
Unknown
Registered
2022-06-21
Start date
2022-06-08
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial plastic surgery

Interventions

treatment group :alfentanil 6µg/kg and remimazolam 0.12 mg/kg
control group:alfentanil 6 µg/kg and propofol 1 mg/kg

Sponsors

Hangzhou Plastic Surgery Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Those who plan to undergo outpatient facial plastic surgery; 2. Age 18-75, regardless of gender; 3. Body mass index (BMI): 18.5-30 kg/m^2; 4. American Society of Anesthesiologists Grading (ASA): I~II; 5. The subjects voluntarily signed the informed consent for this study.

Exclusion criteria

Exclusion criteria: 1. Currently suffering from acute or chronic diseases and taking relevant drugs; 2. Two weeks before the operation had been drinking, smoking, long-term alcoholism; 3. Patients who used sedatives and antiemetic drugs 24 hours before surgery; 4. Suspected abuse of narcotic analgesics or sedatives; 5. Previous history of abnormal operation and anesthesia recovery; 6. Allergic to opioids, benzodiazepines, propofol and excipients; 7. Pregnant women or parturients with pregnancy planning; 8. Participated in other drug trials within three months; 9. Subjects deemed unsuitable for this study by researchers.

Design outcomes

Primary

MeasureTime frame
Subject Satisfaction Score (ISAS Score);

Countries

China

Contacts

Public ContactYunpig Huang
hypxzd@163.com+86 13867420976

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026