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Effect and mechanism of tumor-associated mesenchymal cell exosomes on ferroptosis in pancreatic cancer cells

Effect and mechanism of tumor-associated mesenchymal cell exosomes on ferroptosis in pancreatic cancer cells

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061320
Enrollment
Unknown
Registered
2022-06-20
Start date
2020-08-13
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

control:do not intervene
Induced group:Drug induction with gemcitabine

Sponsors

Tongji Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
43 Years to 68 Years

Inclusion criteria

Inclusion criteria: 1. Patients who underwent radical resection of pancreatic cancer in Shanghai Tongji Hospital; 2. Postoperative pathology confirmed PDAC; 3. Informed before surgery and volunteered to participate in the experiment.

Exclusion criteria

Exclusion criteria: 1. Any form of chemotherapy before surgery; 2. There is distant metastasis of tumor; 3. Associated with pancreatic neuroendocrine tumors.

Design outcomes

Primary

MeasureTime frame
ferroptosis sensitivity;

Countries

China

Contacts

Public ContactBaomin Shi

Tongji Hospital Affiliated to Tongji University

baominsph@163.com+86 18019178695

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026