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Diagnostic and prognostic analysis of haemophagocytic lymphohistiocytic hyperplasia (HLH) in children: a cohort study

Diagnostic and prognostic analysis of haemophagocytic lymphohistiocytic hyperplasia (HLH) in children: a cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061315
Enrollment
Unknown
Registered
2022-06-20
Start date
2022-06-12
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemophagocytic lymphohistiocytosis

Interventions

Death roup:none
Survival group:none

Sponsors

Children's Hospital affiliated to Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. 2010.1.1-2021.12.31 Patients diagnosed or suspected of having HLH by a clinician. 2. Age at first diagnosis: 1-18 years.

Exclusion criteria

Exclusion criteria: 1. Macrophage activation syndrome; 2. Malignancy as the primary disease.

Design outcomes

Primary

MeasureTime frame
Survival time;—

Secondary

MeasureTime frame
Hscore;HLH-related gene mutations;Duration of fever;Total cholesterol;Urea nitrogen;Triglycerides;High-density lipoprotein cholesterol;Low-density lipoprotein- cholesterol;Aspartate transaminase;Alanine transaminase;Lactate dehydrogenase;Gamma-glutamyl transpeptidase;Activated partial thromboplastin time;prothrombin time;Thrombin time;International normalized ratio;Central nervous system hemophagocytic lymphohistiocytosis;—

Countries

China

Contacts

Public ContactLi Xiao

Children’s Hospital of Chongqing Medical University

254606573@qq.com+86 15823373609

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026