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Clinical study on the block time of spinal anesthesia with different doses of ropivacaine

Clinical study on the block time of spinal anesthesia with different doses of ropivacaine

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061260
Enrollment
Unknown
Registered
2022-06-18
Start date
2022-06-12
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia/lower extremity surgery

Interventions

A group:Ropivacaine dose 5 mg
B group:Ropivacaine dose 10 mg
C group:Ropivacaine dose 15 mg
D group:Ropivacaine dose 20 mg

Sponsors

Affiliated Hospital of Yan'an University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The age is 18 -65 years old, regardless of gender, with ASA grade I-III and BMI of 18.5-25.0 kg/m2; 2. No contraindications for spinal anesthesia; 3. No history of local anesthetic allergy; 4. No serious systemic diseases; 5. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Postoperative case follow-up data lost or incomplete; 2. Patients who changed the operation method or anesthesia method during the operation; 3. The operation time lasts more than 2 hours.

Design outcomes

Primary

MeasureTime frame
duration of anesthesia;

Secondary

MeasureTime frame
Onset time of anesthesia;duration of sensory and motor block;intraoperative muscle laxity score;The time for the muscle strength of the operative side to decrease from V to different levels after anesthesia;Surgical side limb block rate;The plane of highest sensation and pain disappearance;tourniquet reaction;BP, HR, number of vasoactive drugs used;muscle recovery time;First time out of bed;The time of the first anal exhaust after surgery;The time of the first water and food after the operation;Postoperative urinary catheter indwelling time;Incidence of nausea and vomiting within 2 days after surgery;Intraoperative urine volume and infusion volume;Operation time;

Countries

China

Contacts

Public ContactZhang Erfei

Affiliated Hospital of Yan'an University

zhangerfei09@126.com+86 13891170975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026