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The effect and mechanism of intermittent theta burst stimulation of cerebellar vermis on balance function in stroke patients

The effect and mechanism of intermittent theta burst stimulation of cerebellar vermis on balance function in stroke patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061225
Enrollment
Unknown
Registered
2022-06-16
Start date
2022-07-15
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group:iTBS + Physiotherapy
Control group:sham iTBS + Physiotherapy

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with cerebral infarction or cerebral hemorrhage; 2. Age between 18-65 years; 3. The first onset and in the subacute stage, the course of the disease is 2 weeks to 6 months; 4. Unilateral stroke must be confirmed by brain computerized tomography or magnetic resonance imaging; 5. There is balance dysfunction; 6. Agree to participate in the trial and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. There are other neurological diseases (including craniocerebral trauma) other than stroke; 2. Cerebellum or brainstem injury; 3. Subjects with TMS contraindications, such as intracranial metal implants or skull defects; 4. Severe cognitive or speech impairment; 5. Combined with heart, lung, liver, kidney and other important organ dysfunction or other serious physical diseases.

Design outcomes

Primary

MeasureTime frame
Berg Balance Scale;

Secondary

MeasureTime frame
Fugl-Meyer assessment scale for lower extremity;Trunk Impairment Scale;Balance Meter Evaluation;Surface electromyography;Functional near-infrared spectroscopy;Transcranial magnetic stimulation with electroencephalogram;Resting-state functional magnetic imaging;Barthel Index;

Countries

China

Contacts

Public ContactQiang Gao

West China Hospital of Sichuan University

gaoqiang_hxkf@163.com+86 18980605992

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026