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Effects of Enhanced External Counterpulsation Versus Aerobic Training on Cardiorespiratory Fitness in Patients with Chronic Coronary Syndrome: A Randomized Study

Effects of Enhanced External Counterpulsation Versus Aerobic Training on Cardiorespiratory Fitness in Patients with Chronic Coronary Syndrome: A Randomized Study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061220
Enrollment
Unknown
Registered
2022-06-16
Start date
2022-02-15
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Coronary Syndrome

Interventions

Group 1 :Coronary heart disease education
Group 3:Enhanced external couterpulsation

Sponsors

The Eighth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Acute coronary syndrome (ACS) occurs within 1 year and the symptoms are stable for more than 4 weeks, or complete revascularization is performed within 1 year (angina pectoris grade CCSI-II), and complete revascularization is performed within 1 year, and the standard of coronary heart disease has been accepted Drug treatment for more than 4 weeks; 2. The patient is 30-65 years old; 3. Sports risk stratification is low, medium risk; 4. LVEF >= 50%; 5. Have not done EECP treatment in the past 3 months.

Exclusion criteria

Exclusion criteria: 1. Severe aortic valve insufficiency; 2. Dissecting aneurysm; 3. Significant pulmonary hypertension; 4. Various bleeding disorders or bleeding tendencies, or use of anticoagulants, INR > 2.0; 5. Various heart valve diseases or congenital heart disease with cardiac insufficiency; 6. Active phlebitis and venous thrombosis cannot cooperate with treatment; 7. There are infection foci in counterpulsation limbs; 8. Uncontrolled hyperemia (170/110 mmHg); 9. Uncontrolled arrhythmia; 10. Acute myocarditis and pericarditis; symptomatic aortic stenosis; severe obstructive hypertrophic cardiomyopathy; acute or severe heart failure; unstable angina; acute myocardial infarction within 4 weeks; chronic obstructive pulmonary disease; those who are affected by other serious diseases or physical activity disorders; those who cannot cooperate with the treatment, questionnaire survey or research plan; those who have participated in other research projects in the past 3 months; the glomerular filtration rate <= 30 ml/min; claustrophobia.

Design outcomes

Primary

MeasureTime frame
peak O2;

Secondary

MeasureTime frame
heart rate variability;global longitudinal strain;myocardial fibrosis;flow mediated dilation value;pulse wave velocity;quality of life;mental state;quality of life;Proteomics;high-sensitivity C-reactive protein;Nitric oxide metabolites;endothelial nitric oxide synthase;interleukin-6;Tumor necrosis factor-a;Superoxide dismutase;

Countries

China

Contacts

Public ContactGuifu Wu

The Eighth Affiliated Hospital of Sun Yat-sen University

wuguifu@mail.sysu.edu.cn+86 15989893111

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026